ABCB8 Antibody (N-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP6129a
Background:
ABCB8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. The protein may also play a role in the transport of phospholipids into mitochondrial membranes.
Other Names: ATP-binding cassette sub-family B member 8, mitochondrial, Mitochondrial ATP-binding cassette 1, M-ABC1, ABCB8, MABC1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6129a was selected from the N-term region of human ABCB8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q9NUT2
Gene ID: 11194
Gene Name: ABCB8 {ECO:0000303|PubMed:25944712, ECO:0000312|HGNC:HGNC:49}
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Saito S., Iida A., Sekine A.J. Hum. Genet. 47:38-50(2002)
ABCB8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. The protein may also play a role in the transport of phospholipids into mitochondrial membranes.
Other Names: ATP-binding cassette sub-family B member 8, mitochondrial, Mitochondrial ATP-binding cassette 1, M-ABC1, ABCB8, MABC1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6129a was selected from the N-term region of human ABCB8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q9NUT2
Gene ID: 11194
Gene Name: ABCB8 {ECO:0000303|PubMed:25944712, ECO:0000312|HGNC:HGNC:49}
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Saito S., Iida A., Sekine A.J. Hum. Genet. 47:38-50(2002)
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