ABCD4 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP9267c
Background:
ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis.
Other Names:
ATP-binding cassette sub-family D member 4, PMP70-related protein, P70R, Peroxisomal membrane protein 1-like, PXMP1-L, Peroxisomal membrane protein 69, PMP69, ABCD4, PXMP1L
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9267c was selected from the Center region of human ABCD4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ABCD4 (HGNC:68)
Gene ID: 5826
Primary Accession: O14678
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis.
Other Names:
ATP-binding cassette sub-family D member 4, PMP70-related protein, P70R, Peroxisomal membrane protein 1-like, PXMP1-L, Peroxisomal membrane protein 69, PMP69, ABCD4, PXMP1L
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9267c was selected from the Center region of human ABCD4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ABCD4 (HGNC:68)
Gene ID: 5826
Primary Accession: O14678
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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