ABCF3 polyclonal, anti-human, rat
€305.00
In stock
SKU
BS60112
Background:
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. As the largest family of transmembrane proteins, ABC peptides comprise several subfamilies. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell, as part of a metabolic process, or outside the cell, for transport to other organs or for secretion from the body. The gene encoding ABCF3 maps to a region that correlates with cervical cancer. Also, high expression levels of ABCF3 have been found in cells of melanocytic origin, suggesting a role for ABCF3 in tumorigenesis. Two isoforms of ABCF3 exist due to alternative splicing events.
Alternative Name:
ATP-binding cassette sub-family F member 3
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: ABCF3 polyclonal antibody detects endogenous levels of ABCF3 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human ABCF3.
MW: ~ 80 kDa
Swis Prot.: Q9NUQ8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. As the largest family of transmembrane proteins, ABC peptides comprise several subfamilies. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell, as part of a metabolic process, or outside the cell, for transport to other organs or for secretion from the body. The gene encoding ABCF3 maps to a region that correlates with cervical cancer. Also, high expression levels of ABCF3 have been found in cells of melanocytic origin, suggesting a role for ABCF3 in tumorigenesis. Two isoforms of ABCF3 exist due to alternative splicing events.
Alternative Name:
ATP-binding cassette sub-family F member 3
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: ABCF3 polyclonal antibody detects endogenous levels of ABCF3 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human ABCF3.
MW: ~ 80 kDa
Swis Prot.: Q9NUQ8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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