ABCG1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5596
Background:
ABCG1 (also designated ABC8 or human white gene), a member of the evolutionary conserved family of ATP-binding cassette (ABC) transporters, exhibits high homology with the Drosophila white gene. ABC transporters couple the energy of ATP hydrolysis to the translocation of various molecules across biological membranes. These proteins contain characteristic ATP-binding domains and transmembrane domains which form a channel-like structure for transport. ABCG1 functions to regulate cholesterol and phospholipid transport in macrophages. ABCG1 is highly expressed in several tissues, including brain, spleen, lung and placenta, and has been localized to the cell surface and intracellular compartments of cholesterol-laden macrophages.
Alternative Name:
ATP-binding cassette sub-family G member 1, ATP-binding cassette transporter 8, White protein homolog, ABC8, WHT1
Application Dilution: WB: 1:500~1:1000
Specificity: ABCG1 polyclonal antibody detects endogenous levels of ABCG1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 633-678 of Human ABCG1.
MW: ~ 110 kDa
Swis Prot.: P45844
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
ABCG1 (also designated ABC8 or human white gene), a member of the evolutionary conserved family of ATP-binding cassette (ABC) transporters, exhibits high homology with the Drosophila white gene. ABC transporters couple the energy of ATP hydrolysis to the translocation of various molecules across biological membranes. These proteins contain characteristic ATP-binding domains and transmembrane domains which form a channel-like structure for transport. ABCG1 functions to regulate cholesterol and phospholipid transport in macrophages. ABCG1 is highly expressed in several tissues, including brain, spleen, lung and placenta, and has been localized to the cell surface and intracellular compartments of cholesterol-laden macrophages.
Alternative Name:
ATP-binding cassette sub-family G member 1, ATP-binding cassette transporter 8, White protein homolog, ABC8, WHT1
Application Dilution: WB: 1:500~1:1000
Specificity: ABCG1 polyclonal antibody detects endogenous levels of ABCG1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 633-678 of Human ABCG1.
MW: ~ 110 kDa
Swis Prot.: P45844
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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