ABI3BP polyclonal, anti-human
€388.00
In stock
SKU
BS72059
Background:
TARSH [ABI family, member 3 (NESH) binding protein], whose alternative names include target of Nesh-SH3, Nesh-binding protein, ABI gene family member 3-binding protein, NESHBP, FLJ41743, FLJ41754 or ABI3BP, is a 1,075 amino acid protein involved in cellular senescence and tumor suppression. Loss of TARSH expression may play a role in the pathogenesis of cancer, especially in thyroid and lung. TARSH acts as a signal transduction molecule and is presumed to interact with with Abi-3, a protein involved in inhibition of ectopic metastasis of tumor cells. TARSH is expressed in brain, lung, heart, liver, placenta, pancreas and kidney, and four TARSH isoforms exist as a result of alternative splicing. TARSH contains a SH3 binding motif and a nuclear targeting sequence.
Alternative Name:
NESHBP, TARSH
Application Dilution: WB: 1:500 - 1:2000
Specificity: ABI3BP polyclonal antibody detects endogenous levels of ABI3BP protein.
Immunogen:
Recombinant protein of human ABI3BP
MW: 118kDa
Swis Prot.: Q7Z7G0
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
TARSH [ABI family, member 3 (NESH) binding protein], whose alternative names include target of Nesh-SH3, Nesh-binding protein, ABI gene family member 3-binding protein, NESHBP, FLJ41743, FLJ41754 or ABI3BP, is a 1,075 amino acid protein involved in cellular senescence and tumor suppression. Loss of TARSH expression may play a role in the pathogenesis of cancer, especially in thyroid and lung. TARSH acts as a signal transduction molecule and is presumed to interact with with Abi-3, a protein involved in inhibition of ectopic metastasis of tumor cells. TARSH is expressed in brain, lung, heart, liver, placenta, pancreas and kidney, and four TARSH isoforms exist as a result of alternative splicing. TARSH contains a SH3 binding motif and a nuclear targeting sequence.
Alternative Name:
NESHBP, TARSH
Application Dilution: WB: 1:500 - 1:2000
Specificity: ABI3BP polyclonal antibody detects endogenous levels of ABI3BP protein.
Immunogen:
Recombinant protein of human ABI3BP
MW: 118kDa
Swis Prot.: Q7Z7G0
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review