ABL1 Antibody Blocking Peptide
€293.00
In stock
SKU
AC-BP3018d
Background:
ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. The peptide used to generate this antibody is 100% conserved between ABL2 and ABL1.
Other Names: Abelson tyrosine-protein kinase , Abelson murine leukemia viral oncogene homolog , ABL1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3018d was selected from the Y251 region of human ABL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P00519
Other Accession: P42684
Gene ID: 25
Gene Name: ABL1
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Cao, C., et al., Biochemistry 42(35):10348-10353 (2003).Cao, C., et al., J. Biol. Chem. 278(32):29667-29675 (2003).Kruh, G.D., et al., Proc. Natl. Acad. Sci. U.S.A. 87(15):5802-5806 (1990).Kruh, G.D., et al., Science 234(4783):1545-1548 (1986).Bianchi, C., et al., FEBS Lett. 527 (1-3), 216-222 (2002).
ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. The peptide used to generate this antibody is 100% conserved between ABL2 and ABL1.
Other Names: Abelson tyrosine-protein kinase , Abelson murine leukemia viral oncogene homolog , ABL1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3018d was selected from the Y251 region of human ABL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P00519
Other Accession: P42684
Gene ID: 25
Gene Name: ABL1
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Cao, C., et al., Biochemistry 42(35):10348-10353 (2003).Cao, C., et al., J. Biol. Chem. 278(32):29667-29675 (2003).Kruh, G.D., et al., Proc. Natl. Acad. Sci. U.S.A. 87(15):5802-5806 (1990).Kruh, G.D., et al., Science 234(4783):1545-1548 (1986).Bianchi, C., et al., FEBS Lett. 527 (1-3), 216-222 (2002).
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