ABL2 antibody (clone 5C6), anti-human
€435.00
In stock
SKU
AC-AT1014a
Catalog Number: AC-AT1014a
Size: 100 µg
Isotype: mouse IgG3 Kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG3 Kappa
Applications: WB, IHC, IF, E
Request Information AC-AT1014a">Request Information
Background:
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Other Names:
Abelson tyrosine-protein kinase 2, Abelson murine leukemia viral oncogene homolog 2, Abelson-related gene protein, Tyrosine-protein kinase ARG, ABL2, ABLL, ARG
Antigen Type:
Recombinant Protein
Gene Name: ABL2
Gene ID: 27
NCBI Accession: NP_001129472.1;NP_001129473.1;NP_001161708.1;NP_001161709.1;NP_001161710.1;NP_001161711.1;NP_005149.4;NP_009298.1
Primary Accession: P42684
Other Accession: BC065912
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Other Names:
Abelson tyrosine-protein kinase 2, Abelson murine leukemia viral oncogene homolog 2, Abelson-related gene protein, Tyrosine-protein kinase ARG, ABL2, ABLL, ARG
Antigen Type:
Recombinant Protein
Gene Name: ABL2
Gene ID: 27
NCBI Accession: NP_001129472.1;NP_001129473.1;NP_001161708.1;NP_001161709.1;NP_001161710.1;NP_001161711.1;NP_005149.4;NP_009298.1
Primary Accession: P42684
Other Accession: BC065912
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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