ABL2 (clone 1H1), anti-human

Protein Family: Protein Kinases

Pathway and Disease: Signal Transduction

Description:
ABL2 (Tyrosine-protein kinase ABL2) regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. ABL2 localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. ABL2 phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.

Alternate Names: ABL2, Tyrosine-protein kinase ABL2, Abelson murine leukemia viral oncogene homolog 2, Abelson-related gene protein, Tyrosine-protein kinase ARG, ABLL, ARG

Application Notes: E: 1:10000; WB: 1:500-1:2000; IF: 1:200-1:1000

Accession No.: P42684

Antigen: Purified recombinant fragment of ABL2 expressed in E. coli.

Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.