ACACA antibody (clone 6H5), anti-human
€435.00
In stock
SKU
AC-AT1018a
Catalog Number: AC-AT1018a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT1018a">Request Information
Background:
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Other Names:
Acetyl-CoA carboxylase 1, ACC1, ACC-alpha, Biotin carboxylase, ACACA, ACAC, ACC1, ACCA
Antigen Type:
Recombinant Protein
Gene Name: ACACA (HGNC:84)
Gene ID: 31
NCBI Accession: NP_942131.1;NP_942133.1;NP_942134.1;NP_942135.1;NP_942136.1
Primary Accession: Q13085
Other Accession: NM_198834
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Other Names:
Acetyl-CoA carboxylase 1, ACC1, ACC-alpha, Biotin carboxylase, ACACA, ACAC, ACC1, ACCA
Antigen Type:
Recombinant Protein
Gene Name: ACACA (HGNC:84)
Gene ID: 31
NCBI Accession: NP_942131.1;NP_942133.1;NP_942134.1;NP_942135.1;NP_942136.1
Primary Accession: Q13085
Other Accession: NM_198834
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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