ACCα (phospho Ser80) Polyclonal Antibody

Background:
acetyl-CoA carboxylase alpha(ACACA) Homo sapiens Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Alternative Names:
ACACA, ACAC, ACC1, ACCA, Acetyl-CoA carboxylase 1, ACC1, ACC-alpha

Immunogen: The antiserum was produced against synthesized peptide derived from human ACC1 around the phosphorylation site of Ser80. AA range:46-95

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 265

GeneID: ACACA

Storage: -20°C/1 year

NOTE: For Research Use Only