ACE Antibody (C-term) Blocking Peptide

ACE Antibody (C-term) Blocking Peptide

€293.00
In stock
SKU
AC-BP7793b
Catalog Number: AC-BP7793b
Size: 500 µg
Datasheet

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Background:
ACE is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active.

Other Names: Angiotensin-converting enzyme, ACE, 321-, Dipeptidyl carboxypeptidase I, Kininase II, CD143, Angiotensin-converting enzyme, soluble form, ACE, DCP, DCP1

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7793b was selected from the C-term region of human ACE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Type: Synthetic peptide

Primary Accession: P12821

Gene ID: 1636

Gene Name: ACE

Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Bio References:
du Cheyron,D.,Crit. Care Med. 36 (12), 3178-3183 (2008)Pang,S., Biochem. J. 358 (PT 1), 185-192 (2001)Woodman,Z.L., Biochem. J. 347 PT 3, 711-718 (2000)
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