Acetyl Histone H2A (K5) Polyclonal Antibody

Acetyl Histone H2A (K5) Polyclonal Antibody

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In stock
SKU
ELK-ES5713
Catalog Number: ELK-ES5713
Reactivity: Human, Mouse, Rat
Applications: IHC-p, WB, ELISA
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Background:
H2A histone family member Z(H2AFZ) Homo sapiens Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],

Alternative Names:
H2AFZ, H2AZ, Histone H2A.Z, H2A/z

Immunogen: The antiserum was produced against synthesized peptide derived from human Histone H2A around the acetylated site of Lys5. AA range:1-50

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 14

GeneID: H2AFZ

Storage: -20°C/1 year

NOTE: For Research Use Only
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