Acetylcholinesterase (clone 12B4), anti-human
€747.00
In stock
SKU
250342
Catalog Nr.: 250342
Size: 0.2 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Size: 0.2 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Protein Family: Enzymes, Peptidase
Pathway and Disease: Nervous and Sensory Systems, Signal Transduction
Description:
Acetylcholinesterase (AChE, EC.3.1.1.7.) is an enzyme located in the postsynaptic membrane and in the muscle endplates, where it hydrolyses the neurotransmitter acetylcholin. AChE from brain is a tetramer (G4-AChE) with a molecular mass of 320 kDa, AChE from erythrocytes is a dimer (G2-AChE) with a molecular mass of 170 kDa. This antibody is specific for human acetylcholinesterase. No cross-reaction is seen with human BtChE and AChE from flounder or Torpedo marmorata.
Alternate Names: AChE
Application Notes: Product Cat. No. 250342 reacts with both G2-and G4-AChE (native detergent soluble) in ELISA and EAIA using the antibody as capture antibody. Product Cat. No. 250342 reacts 17-fold stronger with human brain AChE than with human erythrocyte AChE. E: 1:4,000; WB: 1:500
Accession No.: P22303
Antigen: Brain acetylcholinesterase, human, purified and detergent solubilized (1).
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems, Signal Transduction
Description:
Acetylcholinesterase (AChE, EC.3.1.1.7.) is an enzyme located in the postsynaptic membrane and in the muscle endplates, where it hydrolyses the neurotransmitter acetylcholin. AChE from brain is a tetramer (G4-AChE) with a molecular mass of 320 kDa, AChE from erythrocytes is a dimer (G2-AChE) with a molecular mass of 170 kDa. This antibody is specific for human acetylcholinesterase. No cross-reaction is seen with human BtChE and AChE from flounder or Torpedo marmorata.
Alternate Names: AChE
Application Notes: Product Cat. No. 250342 reacts with both G2-and G4-AChE (native detergent soluble) in ELISA and EAIA using the antibody as capture antibody. Product Cat. No. 250342 reacts 17-fold stronger with human brain AChE than with human erythrocyte AChE. E: 1:4,000; WB: 1:500
Accession No.: P22303
Antigen: Brain acetylcholinesterase, human, purified and detergent solubilized (1).
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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