AChRα1 polyclonal, anti-human, mouse

AChRα1 polyclonal, anti-human, mouse

€388.00
In stock
SKU
BS6951
Catalog Number: BS6951
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB

Datasheet
Background:
Nicotinic acetylcholine receptors(AChRs) are found at the postsynaptic membrane of the neuromuscular junctionand bind acetylcholine molecules, allowing ions to move through thepore. Glutamate receptors are found in the postsynaptic membrane of cellsin the central nervous system. AChRα1, also known as ACHRD, CHRNA, CMS2A, FCCMS, SCCMS or CHRNA1, is a 482 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms, which are expressed in different tissues. Isoform 1 is only expressed in skeletal muscle whereas isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus.

Alternative Name:
Acetylcholine receptor subunit alpha, ACHRA, CHNRA, CHRNA1, ACHRD, CMS2A, FCCMS, SCCMS, Acra

Application Dilution: WB: 1:500 - 1:2000

Specificity: AChRα1 polyclonal antibody detects endogenous levels of AChRα1 protein.

Immunogen:
Recombinant full length Human AChRα1.

MW: ~ 66 kDa

Swis Prot.: P02708

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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