AChRα5 polyclonal, anti-human, mouse

AChRα5 polyclonal, anti-human, mouse

€388.00
In stock
SKU
BS6567
Catalog Number: BS6567
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB

Datasheet
Background:
Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChRα5, also known as LNCR2 or CHRNA5 (cholinergic receptor, nicotinic, alpha 5), is a 468 amino acid multi-pass membrane protein belonging to the ligand-gated ionic channel family and is involved in the mediation of fast signal transmission at synapses.

Alternative Name:
ACHA5, alpha polypeptide 5, cholinergic receptor, Cholinergic receptor neuronal nicotinic alpha polypeptide 5, Cholinergic receptor nicotinic alpha 5, Cholinergic receptor nicotinic alpha polypeptide 5, CHRNA 5, CHRNA5, LNCR2, NACHRA 5, NACHRA5, Neuronal acetylcholine receptor subunit alpha 5, Neuronal acetylcholine receptor subunit alpha-5, Neuronal nicotinic acetylcholine receptor alpha 5 subunit, Neuronal nicotinic acetylcholine receptor, alpha5 subunit, nicotinic,

Application Dilution: WB: 1:500 - 1:2000

Specificity: AChRα5 polyclonal antibody detects endogenous levels of AChRα5 protein.

Immunogen:
Recombinant full length Human AChRα5.

MW: ~ 53 kDa

Swis Prot.: P30532

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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