AChRα7 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60391
Background:
Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome. CHRFAM7A, a fusion protein comprised of FAM7A and AChRα7, is encoded by the CHRFAM7A gene, which is located on a region of human chromosome 15 that is associated with several neuropsychiatric disorders, such as schizophrenia and bipolar affective disorder. CHRFAM7A, also known as D-10 or CHRNA7, is a 412 amino acid multi-pass membrane protein that belongs to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, a protein superfamily that mediates signal transmission at synapses. CHRFAM7A is expressed in the hippocampus. Alternative splicing of the CHRFAM7A gene produces two splice variants.
Alternative Name:
Neuronal acetylcholine receptor subunit alpha-7, CHRNA7, NACHRA7, CHRNA7-FAM7A fusion protein, CHRNA7-DR1, D-10, CHRFAM7A
Application Dilution: WB: 1:500~1:1000
Specificity: AChRα7 polyclonal antibody detects endogenous levels of AChRα7 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human AChRα7.
MW: ~ 50 kDa
Swis Prot.: P36544/Q494W8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome. CHRFAM7A, a fusion protein comprised of FAM7A and AChRα7, is encoded by the CHRFAM7A gene, which is located on a region of human chromosome 15 that is associated with several neuropsychiatric disorders, such as schizophrenia and bipolar affective disorder. CHRFAM7A, also known as D-10 or CHRNA7, is a 412 amino acid multi-pass membrane protein that belongs to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, a protein superfamily that mediates signal transmission at synapses. CHRFAM7A is expressed in the hippocampus. Alternative splicing of the CHRFAM7A gene produces two splice variants.
Alternative Name:
Neuronal acetylcholine receptor subunit alpha-7, CHRNA7, NACHRA7, CHRNA7-FAM7A fusion protein, CHRNA7-DR1, D-10, CHRFAM7A
Application Dilution: WB: 1:500~1:1000
Specificity: AChRα7 polyclonal antibody detects endogenous levels of AChRα7 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human AChRα7.
MW: ~ 50 kDa
Swis Prot.: P36544/Q494W8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review