ACK (phospho Tyr284) Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES4434
Catalog Number: ELK-ES4434
Reactivity: Human, Mouse
Applications: WB, IHC-p, IF, ELISA
Information
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Reactivity: Human, Mouse
Applications: WB, IHC-p, IF, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
tyrosine kinase non receptor 2(TNK2) Homo sapiens This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008],
Alternative Names:
TNK2, ACK1, Activated CDC42 kinase 1, ACK-1, Tyrosine kinase non-receptor protein 2
Immunogen: The antiserum was produced against synthesized peptide derived from human ACK1 around the phosphorylation site of Tyr284. AA range:250-299
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 120
GeneID: TNK2
Storage: -20°C/1 year
NOTE: For Research Use Only
tyrosine kinase non receptor 2(TNK2) Homo sapiens This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008],
Alternative Names:
TNK2, ACK1, Activated CDC42 kinase 1, ACK-1, Tyrosine kinase non-receptor protein 2
Immunogen: The antiserum was produced against synthesized peptide derived from human ACK1 around the phosphorylation site of Tyr284. AA range:250-299
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 120
GeneID: TNK2
Storage: -20°C/1 year
NOTE: For Research Use Only
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