ACSL5 (FACL5) Antibody (N-term) Blocking peptide
€293.00
In stock
SKU
AC-BP2536a
Background:
Long chain acyl-CoA synthetase (LACS), or long chain fatty acid-CoA ligases (FACLs), convert free long chain fatty acids into fatty acyl-CoA esters, which are key intermediates in the synthesis of complex lipids. The deduced 683-amino acid FACL5 protein shares approximately 80% amino acid identity with the rat sequence. Northern blot analysis detected major FACL5 transcripts of 2.5 and 3.7 kb in a many tissues, with highest expression in uterus and spleen. Markedly increased levels of FACL5 transcripts are detected in a glioma line and in primary gliomas of grade IV malignancy, Cultured glioma cells infected with an adenovirus encoding FACL5 displayed induced cell growth on exposure to palmitate. These results suggest a novel fatty acid-induced glioma cell growth mediated by FACL5.
Other Names: Long-chain-fatty-acid--CoA ligase 5, Long-chain acyl-CoA synthetase 5, LACS 5, ACSL5, ACS5, FACL5
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2536a was selected from the N-term region of human FACL5 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q9ULC5
Other Accession: ACSL5_HUMAN
Gene ID: 51703
Gene Name: ACSL5 (HGNC:16526)
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Long chain acyl-CoA synthetase (LACS), or long chain fatty acid-CoA ligases (FACLs), convert free long chain fatty acids into fatty acyl-CoA esters, which are key intermediates in the synthesis of complex lipids. The deduced 683-amino acid FACL5 protein shares approximately 80% amino acid identity with the rat sequence. Northern blot analysis detected major FACL5 transcripts of 2.5 and 3.7 kb in a many tissues, with highest expression in uterus and spleen. Markedly increased levels of FACL5 transcripts are detected in a glioma line and in primary gliomas of grade IV malignancy, Cultured glioma cells infected with an adenovirus encoding FACL5 displayed induced cell growth on exposure to palmitate. These results suggest a novel fatty acid-induced glioma cell growth mediated by FACL5.
Other Names: Long-chain-fatty-acid--CoA ligase 5, Long-chain acyl-CoA synthetase 5, LACS 5, ACSL5, ACS5, FACL5
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2536a was selected from the N-term region of human FACL5 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q9ULC5
Other Accession: ACSL5_HUMAN
Gene ID: 51703
Gene Name: ACSL5 (HGNC:16526)
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
| Is Featured? | No |
|---|
Write Your Own Review