Actin-κ (T121) polyclonal, anti-human, mouse
€305.00
In stock
SKU
BS9201
Background:
All eukaryotic cells express Actin, which often constitutes as much as 50% of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one Actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of Actin are present in mammalian tissues and fall into three classes. Members of the small GTPase family regulate the organization of the Actin cytoskeleton. Rho controls the assembly of Actin stress fibers and focal adhesion. Rac regulates Actin filament accumulation at the plasma membrane. Cdc42 stimulates formation of filopodia.
Alternative Name:
Putative beta-actin-like protein 3, Kappa-actin, POTE ankyrin domain family member K, FKSG30, ACTBL3, POTEKP
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Actin-κ (T121) polyclonal antibody detects endogenous levels of Actin-κ protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 90-134 of Human Actin-κ.
MW: ~ 42 kDa
Swis Prot.: Q9BYX7
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
All eukaryotic cells express Actin, which often constitutes as much as 50% of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one Actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of Actin are present in mammalian tissues and fall into three classes. Members of the small GTPase family regulate the organization of the Actin cytoskeleton. Rho controls the assembly of Actin stress fibers and focal adhesion. Rac regulates Actin filament accumulation at the plasma membrane. Cdc42 stimulates formation of filopodia.
Alternative Name:
Putative beta-actin-like protein 3, Kappa-actin, POTE ankyrin domain family member K, FKSG30, ACTBL3, POTEKP
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Actin-κ (T121) polyclonal antibody detects endogenous levels of Actin-κ protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 90-134 of Human Actin-κ.
MW: ~ 42 kDa
Swis Prot.: Q9BYX7
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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