Activated Protein C polyclonal, anti-human, mouse, rat, pig, dog, bovine, chicken

Protein Family: Enzymes, Peptidases

Pathway and Disease: Immune System

Description:
Activated protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Defects in activated protein C are the cause of protein C deficiency autosomal dominant (ADPROCD) disorder. ADPROCD is a cause of hereditary thrombophilia, a hemostatic disorder characterized by impaired regulation of blood coagulation and a tendency to recurrent venous thrombosis.

Alternate Names: Activated Protein C, Protein C, APC, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: NP_000303

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human activated protein C.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.