Actived-Caspase-9 p35 (D315) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS7070
Background:
Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit.
Alternative Name:
APAF 3,APAF-3,APAF3,Apoptosis related cysteine peptidase,Apoptotic protease activating factor 3,Apoptotic protease Mch 6,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,CASP 9,CASP-9,CASP9, Caspase 9 apoptosis related cysteine peptidase,Caspase 9 Dominant Negative,Caspase 9c,Caspase-9, Caspase9,ICE LAP6,ICE like apoptotic protease 6,ICE-LAP6,ICE-like apoptotic protease 6,MCH6,RNCASP9
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Actived-Caspase-9 p35 (D315) polyclonal antibody detects detects endogenous levels of the 35 kDa large fragment of caspase-9 following cleavage at aspartic acid 315.
Immunogen:
Synthetic peptide, corresponding to amino acids 300-350 of Human Caspase 9.
MW: ~ 35 kDa
Swis Prot.: P55211
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit.
Alternative Name:
APAF 3,APAF-3,APAF3,Apoptosis related cysteine peptidase,Apoptotic protease activating factor 3,Apoptotic protease Mch 6,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,CASP 9,CASP-9,CASP9, Caspase 9 apoptosis related cysteine peptidase,Caspase 9 Dominant Negative,Caspase 9c,Caspase-9, Caspase9,ICE LAP6,ICE like apoptotic protease 6,ICE-LAP6,ICE-like apoptotic protease 6,MCH6,RNCASP9
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Actived-Caspase-9 p35 (D315) polyclonal antibody detects detects endogenous levels of the 35 kDa large fragment of caspase-9 following cleavage at aspartic acid 315.
Immunogen:
Synthetic peptide, corresponding to amino acids 300-350 of Human Caspase 9.
MW: ~ 35 kDa
Swis Prot.: P55211
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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