Activin A human active recombinant protein

Activin A human active recombinant protein

€295.00
In stock
SKU
600339
Catalog Number: 600339
Size: 0.01 mg
Datasheet
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Protein Family: Cytokines

Pathway and Disease: Endocrine System, Signal Transduction, Signaling Molecules and interaction, Nervous and Sensory Systems

Alternate Names: Inhibin beta-1, FRP, FSH-releasing protein, Inhibin beta A chain, Activin A, INHBA, Activin beta-A chain, Erythroid differentiation protein, EDFDescription:
Activin A is a member of the TGF beta family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two beta A chains and is not biologically active until the N terminal propeptide is cleaved from each. Human Activin A has 100% amino acid sequence identity to mouse, rat, porcine, bovine and feline proteins. Human Activin A is produced in E.coli. Non-glycosylated homodimer, containing two 117 amino acid chains, with a total predicted molecular weight of 26.2 kDa.

Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.

Applications: E, WB

Application Notes:
The activity is determined by the ability to induce cytoxicity of MPC-11 cells and is typically less than 2 ng/mL. Specific activity: 5 x 10e5 units/mg

Accession No.: P08476

MW: 26200 Da

Sequence:
MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS

Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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