ACTL6A Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP17002a
Background:
This gene encodes a family member of actin-relatedproteins (ARPs), which share significant amino acid sequenceidentity to conventional actins. Both actins and ARPs have an actinfold, which is an ATP-binding cleft, as a common feature. The ARPsare involved in diverse cellular processes, including vesiculartransport, spindle orientation, nuclear migration and chromatinremodeling. This gene encodes a 53 kDa subunit protein of the BAF(BRG1/brm-associated factor) complex in mammals, which isfunctionally related to SWI/SNF complex in S. cerevisiae andDrosophila; the latter is thought to facilitate transcriptionalactivation of specific genes by antagonizing chromatin-mediatedtranscriptional repression. Together with beta-actin, it isrequired for maximal ATPase activity of BRG1, and for theassociation of the BAF complex with chromatin/matrix. Threetranscript variants that encode two different protein isoforms havebeen described.
Other Names:
Actin-like protein 6A, 53 kDa BRG1-associated factor A, Actin-related protein Baf53a, ArpNbeta, BRG1-associated factor 53A, BAF53A, INO80 complex subunit K, ACTL6A, BAF53, BAF53A, INO80K
Gene Name: ACTL6A
Gene ID: 86
Primary Accession: O96019
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a family member of actin-relatedproteins (ARPs), which share significant amino acid sequenceidentity to conventional actins. Both actins and ARPs have an actinfold, which is an ATP-binding cleft, as a common feature. The ARPsare involved in diverse cellular processes, including vesiculartransport, spindle orientation, nuclear migration and chromatinremodeling. This gene encodes a 53 kDa subunit protein of the BAF(BRG1/brm-associated factor) complex in mammals, which isfunctionally related to SWI/SNF complex in S. cerevisiae andDrosophila; the latter is thought to facilitate transcriptionalactivation of specific genes by antagonizing chromatin-mediatedtranscriptional repression. Together with beta-actin, it isrequired for maximal ATPase activity of BRG1, and for theassociation of the BAF complex with chromatin/matrix. Threetranscript variants that encode two different protein isoforms havebeen described.
Other Names:
Actin-like protein 6A, 53 kDa BRG1-associated factor A, Actin-related protein Baf53a, ArpNbeta, BRG1-associated factor 53A, BAF53A, INO80 complex subunit K, ACTL6A, BAF53, BAF53A, INO80K
Gene Name: ACTL6A
Gene ID: 86
Primary Accession: O96019
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review