ACTL6B Antibody (N-term) Blocking peptide
€293.00
In stock
SKU
AC-BP5327a
Background:
ACTL6B is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.
Other Names: Actin-like protein 6B, 53 kDa BRG1-associated factor B, Actin-related protein Baf53b, ArpNalpha, BRG1-associated factor 53B, BAF53B, ACTL6B, ACTL6, BAF53B
Type: Synthetic peptide
Primary Accession: O94805
Other Accession: NP_057272.1
Gene ID: 51412
Gene Name: ACTL6B (HGNC:160)
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Oma, Y., et al. Biochem. Biophys. Res. Commun. 301(2):521-528(2003)Kuroda, Y., et al. Biochem. Biophys. Res. Commun. 299(2):328-334(2002)Olave, I., et al. Genes Dev. 16(19):2509-2517(2002)
ACTL6B is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.
Other Names: Actin-like protein 6B, 53 kDa BRG1-associated factor B, Actin-related protein Baf53b, ArpNalpha, BRG1-associated factor 53B, BAF53B, ACTL6B, ACTL6, BAF53B
Type: Synthetic peptide
Primary Accession: O94805
Other Accession: NP_057272.1
Gene ID: 51412
Gene Name: ACTL6B (HGNC:160)
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Oma, Y., et al. Biochem. Biophys. Res. Commun. 301(2):521-528(2003)Kuroda, Y., et al. Biochem. Biophys. Res. Commun. 299(2):328-334(2002)Olave, I., et al. Genes Dev. 16(19):2509-2517(2002)
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