ACTL7B Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP16511a
Background:
The protein encoded by this gene is a member of a familyof actin-related proteins (ARPs) which share significant amino acidsequence identity to conventional actins. Both actins and ARPs havean actin fold, which is an ATP-binding cleft, as a common feature.The ARPs are involved in diverse cellular processes, includingvesicular transport, spindle orientation, nuclear migration andchromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A,are intronless, and are located approximately 4 kb apart in ahead-to-head orientation within the familial dysautonomia candidateregion on 9q31. Based on mutational analysis of the ACTL7B gene inpatients with this disorder, it was concluded that it is unlikelyto be involved in the pathogenesis of dysautonomia. Unlike ACTL7A,the ACTL7B gene is expressed predominantly in the testis, however,its exact function is not known.
Other Names:
Actin-like protein 7B, Actin-like-7-beta, ACTL7B
Gene Name: ACTL7B
Gene ID: 10880
Primary Accession: Q9Y614
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of a familyof actin-related proteins (ARPs) which share significant amino acidsequence identity to conventional actins. Both actins and ARPs havean actin fold, which is an ATP-binding cleft, as a common feature.The ARPs are involved in diverse cellular processes, includingvesicular transport, spindle orientation, nuclear migration andchromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A,are intronless, and are located approximately 4 kb apart in ahead-to-head orientation within the familial dysautonomia candidateregion on 9q31. Based on mutational analysis of the ACTL7B gene inpatients with this disorder, it was concluded that it is unlikelyto be involved in the pathogenesis of dysautonomia. Unlike ACTL7A,the ACTL7B gene is expressed predominantly in the testis, however,its exact function is not known.
Other Names:
Actin-like protein 7B, Actin-like-7-beta, ACTL7B
Gene Name: ACTL7B
Gene ID: 10880
Primary Accession: Q9Y614
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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