ACVR1C polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6020
Background:
ACTR-IC (Activin receptor type 1C), also referred to as Activin receptor-like kinase 7 (ALK-7), is a type I serine/threonine kinase receptor. ACTA-IC contains an extracellular binding domain, an intracellular serine/threonine kinase domain preceded by a GS box and a transmembrane domain. It is expressed throughout the digestive and central nervous system and localizes to the cell surface. Four ACTR-IC transcripts are generated by alternative splicing. Transcript 1 is the functional full length receptor, transcript 2 lacks a complete receptor binding domain and transcripts 3 and 4 are soluble proteins that lack a transmembrane domain. ACTR-IC is a receptor for Activin AB, Activin B and Nodal. In pancreatic cells, ACTR-IC forms a complex with Activin receptor type IIB (ACTR-IIB).
Alternative Name:
Activin A receptor, type IC, Activin receptor like kinase 7, Activin receptor type 1C precursor, Activin receptor type IC, Activin receptor type-1C, Activin receptor-like kinase 7, ACTR IC, ACTR-IC, ACTRIC, ACV1C, Acvr1c, ACVRLK7, ALK 7, ALK-7, ALK7,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: ACVR1C polyclonal antibody detects endogenous levels of ACVR1C protein.
Immunogen:
Recombinant full length Human ACVR1C.
MW: ~ 55 kDa
Swis Prot.: Q8NER5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
ACTR-IC (Activin receptor type 1C), also referred to as Activin receptor-like kinase 7 (ALK-7), is a type I serine/threonine kinase receptor. ACTA-IC contains an extracellular binding domain, an intracellular serine/threonine kinase domain preceded by a GS box and a transmembrane domain. It is expressed throughout the digestive and central nervous system and localizes to the cell surface. Four ACTR-IC transcripts are generated by alternative splicing. Transcript 1 is the functional full length receptor, transcript 2 lacks a complete receptor binding domain and transcripts 3 and 4 are soluble proteins that lack a transmembrane domain. ACTR-IC is a receptor for Activin AB, Activin B and Nodal. In pancreatic cells, ACTR-IC forms a complex with Activin receptor type IIB (ACTR-IIB).
Alternative Name:
Activin A receptor, type IC, Activin receptor like kinase 7, Activin receptor type 1C precursor, Activin receptor type IC, Activin receptor type-1C, Activin receptor-like kinase 7, ACTR IC, ACTR-IC, ACTRIC, ACV1C, Acvr1c, ACVRLK7, ALK 7, ALK-7, ALK7,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: ACVR1C polyclonal antibody detects endogenous levels of ACVR1C protein.
Immunogen:
Recombinant full length Human ACVR1C.
MW: ~ 55 kDa
Swis Prot.: Q8NER5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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