ADAMDEC1 polyclonal, anti-human, mouse, rat

ADAMDEC1 polyclonal, anti-human, mouse, rat

€305.00
In stock
SKU
BS61122
Catalog Number: BS61122
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB, IHC

Datasheet
Background:
ADAMDEC1 (ADAM-like, decysin 1), also known as decysin, is a 470 amino acid secreted protein that belongs to the disintegrin metalloproteinase family. Expressed primarily in dendritic cells (DCs) of the small intestine, spleen and lymph nodes, ADAMDEC1 can bind one zinc ion per subunit and is thought to be involved in controlling the immune response. ADAMDEC1 expression is induced in maturing DC cells in response to T-cell signals and its expression is upegulated during differentiation of primary monocytes into macrophages. ADAMDEC1 contains one peptidase M12B domain, a prematurely terminated disintegrin domain and, unlike other ADAM family members, does not have an intracellular tail or a cysteine-rich domain.

Alternative Name:
ADAM DEC1 (EC:3.4.24.-), A disintegrin and metalloproteinase domain-like protein decysin-1, ADAM-like protein decysin-1, ADAMDEC1

Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200

Specificity: ADAMDEC1 polyclonal antibody detects endogenous levels of ADAMDEC1 protein.

Immunogen:
A synthetic peptide corresponding to residues in Human ADAMDEC1.

MW: ~ 53 kDa

Swis Prot.: O15204

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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