ADD1 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13986b
Background:
Adducins are a family of cytoskeleton proteins encoded bythree genes (alpha, beta, gamma). Adducin is a heterodimericprotein that consists of related subunits, which are produced fromdistinct genes but share a similar structure. Alpha- andbeta-adducin include a protease-resistant N-terminal region and aprotease-sensitive, hydrophilic C-terminal region. Alpha- andgamma-adducins are ubiquitously expressed. In contrast,beta-adducin is expressed at high levels in brain and hematopoietictissues. Adducin binds with high affinity to Ca(2+)/calmodulin andis a substrate for protein kinases A and C. Alternative splicingresults in multiple variants encoding distinct isoforms; however,not all variants have been fully described.
Other Names:
Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13986b was selected from the C-term region of ADD1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ADD1
Gene ID: 118
Primary Accession: P35611
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Adducins are a family of cytoskeleton proteins encoded bythree genes (alpha, beta, gamma). Adducin is a heterodimericprotein that consists of related subunits, which are produced fromdistinct genes but share a similar structure. Alpha- andbeta-adducin include a protease-resistant N-terminal region and aprotease-sensitive, hydrophilic C-terminal region. Alpha- andgamma-adducins are ubiquitously expressed. In contrast,beta-adducin is expressed at high levels in brain and hematopoietictissues. Adducin binds with high affinity to Ca(2+)/calmodulin andis a substrate for protein kinases A and C. Alternative splicingresults in multiple variants encoding distinct isoforms; however,not all variants have been fully described.
Other Names:
Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13986b was selected from the C-term region of ADD1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ADD1
Gene ID: 118
Primary Accession: P35611
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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