Adducin α/β (phospho-S726/713) polyclonal, anti-human, mouse, rat
€328.00
In stock
SKU
BS4005
Background:
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
Alternative Name:
Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA, α-Adducin, Adducin1, Adducin-1, α Adducin, Adducin-α, Beta-adducin, Erythrocyte adducin subunit beta, ADD2, ADDB, β-Adducin, Adducin1, Adducin-1, β Adducin, Adducin β, Adducin-β
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: p-Adducin α/β (S726/713) polyclonal antibody detects endogenous levels of Adducin α protein only when phosphorylated at Ser726 and Adducin β protein only when phosphorylated at Ser713.
Immunogen:
Synthetic phosphopeptide derived from human Adducin α around the phosphorylation site of Serine 726.
MW: ~ 81 kDa
Swis Prot.: P35611/P35612
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
Alternative Name:
Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA, α-Adducin, Adducin1, Adducin-1, α Adducin, Adducin-α, Beta-adducin, Erythrocyte adducin subunit beta, ADD2, ADDB, β-Adducin, Adducin1, Adducin-1, β Adducin, Adducin β, Adducin-β
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: p-Adducin α/β (S726/713) polyclonal antibody detects endogenous levels of Adducin α protein only when phosphorylated at Ser726 and Adducin β protein only when phosphorylated at Ser713.
Immunogen:
Synthetic phosphopeptide derived from human Adducin α around the phosphorylation site of Serine 726.
MW: ~ 81 kDa
Swis Prot.: P35611/P35612
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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