Adducin α polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS6511
Background:
Adducins are a family of cytoskeleton proteins encoded by three genes (α, β, γ). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin α is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin α and Adducin γ is ubiquitous in contrast to the restricted expression of Adducin β. Adducin β is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice.
Alternative Name:
Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA, α-Adducin, Adducin1, Adducin-1, α Adducin, Adducin-α
Application Dilution: WB: 1:500 - 1:2000
Specificity: Adducin α polyclonal antibody detects endogenous levels of Adducin α protein.
Immunogen:
Recombinant full length Human Adducin α.
MW: ~ 81 kDa
Swis Prot.: P35611
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Adducins are a family of cytoskeleton proteins encoded by three genes (α, β, γ). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin α is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin α and Adducin γ is ubiquitous in contrast to the restricted expression of Adducin β. Adducin β is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice.
Alternative Name:
Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA, α-Adducin, Adducin1, Adducin-1, α Adducin, Adducin-α
Application Dilution: WB: 1:500 - 1:2000
Specificity: Adducin α polyclonal antibody detects endogenous levels of Adducin α protein.
Immunogen:
Recombinant full length Human Adducin α.
MW: ~ 81 kDa
Swis Prot.: P35611
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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