Adeno-associated virus 6 (AAV6), intact particles (clone ADK6), anti-

Background:
Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. Gene therapy vectors using AAV can infect both dividing and quiescent cells and persist in an extrachromosomal state without integrating into the genome of the host cell. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models

Decription:
For characterization of different stages of infection and very useful for the analysis of the AAV assembly process. ADK6 specifically reacts with intact adeno-associated virus particles, empty and full capsids. Recognizes a conformational epitope of assembled capsids. The antibody cannot be used for immunoblotting.

Clone: ADK6

Isotype: Mouse IgG2a, kappa

Immunogen: Recombinant adeno-associated virus type 6 (AAV-6) vector, carrying GFP

Reactivity: virus

Specificity: Specific for AAV-6, found in human; in immunofluorescence microscopy and dot blot analysis no cross-reaction with AAV type 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, and 12 was observed.

Form: Culture supernatant

Applications: Immunofluorescence microscopy, Immunohistochemistry, Dot blot, ELISA

Working Dilution: Ready-to-use for Immunohistochemistry

Storage: 2-8C