Adipophilin polyclonal, anti-human, mouse, rat

Protein Family: Receptors and Channels

Pathway and Disease: Endocrine System, Cell Growth and Death

Description:
Adipophilin (ADFP, adipocyte differentiation-related protein) is a peripheral membrane located in milk lipid globules. Adipophilin is involved in the development and maintenance of adipose tissue. Adipophilin, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains stoichiometric amounts of butyrophilin and xanthine oxidase. Adipophilin is expressed in a wide range of cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, it is restricted to certain cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty hepatocytes in alcoholic liver cirrhosis. Adipophilin is a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.

Alternate Names: ADFP, ADRP, Adipophilin, Adipose differentiation-related protein, Perilipin-2, PLIN2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: Q99541

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse adipophilin.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.