ADK Antibody (C-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP7091b
Background:
Adenosine kinase is an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.
Other Names: Adenosine kinase, AK, Adenosine 5'-phosphotransferase, ADK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7091b was selected from the C-term region of human ADK . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P55263
Other Accession: NP_006712
Gene ID: 132
Gene Name: ADK
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Szkotak, A.J., et al., J. Membr. Biol. 192(3):169-179 (2003).Singh, B., et al., DNA Cell Biol. 20(1):53-65 (2001).Van Rompay, A.R., et al., Eur. J. Biochem. 261(2):509-517 (1999).Mathews, I.I., et al., Biochemistry 37(45):15607-15620 (1998).McNally, T., et al., Biochem. Biophys. Res. Commun. 231(3):645-650 (1997).
Adenosine kinase is an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.
Other Names: Adenosine kinase, AK, Adenosine 5'-phosphotransferase, ADK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7091b was selected from the C-term region of human ADK . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P55263
Other Accession: NP_006712
Gene ID: 132
Gene Name: ADK
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Szkotak, A.J., et al., J. Membr. Biol. 192(3):169-179 (2003).Singh, B., et al., DNA Cell Biol. 20(1):53-65 (2001).Van Rompay, A.R., et al., Eur. J. Biochem. 261(2):509-517 (1999).Mathews, I.I., et al., Biochemistry 37(45):15607-15620 (1998).McNally, T., et al., Biochem. Biophys. Res. Commun. 231(3):645-650 (1997).
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