ADM polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61561
Background:
Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and the maintenance of cardiovascular functioning, and in hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions and ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and this peptide can exert central effects such as decreasing food ingestion.
Alternative Name:
ADM, AM, ProAM N-terminal 20 peptide, PAMP, ProAM-N2
Application Dilution: WB: 1:500~1:1000
Specificity: ADM polyclonal antibody detects endogenous levels of ADM protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 116-160 of Human ADM
MW: ~ 25 kDa
Swis Prot.: P35318
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and the maintenance of cardiovascular functioning, and in hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions and ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and this peptide can exert central effects such as decreasing food ingestion.
Alternative Name:
ADM, AM, ProAM N-terminal 20 peptide, PAMP, ProAM-N2
Application Dilution: WB: 1:500~1:1000
Specificity: ADM polyclonal antibody detects endogenous levels of ADM protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 116-160 of Human ADM
MW: ~ 25 kDa
Swis Prot.: P35318
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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