ADNP Antibody

Protein Family: Transcription Factors, Enzymes, Receptors and Channels

Pathway and Disease: Cell Growth and Death, Cancers, Transcription

Description:
Activity-dependent Neuroprotective Protein (ADNP) is a potential transcription factor that mediates some of the neuroprotective peptide VIP-associated effects involved in normal growth and cancer proliferation. ADNP is mainly expressed in the cerebellum and hippocampus with lower levels in lung, kidney, intestine and testis. The neuroprotective peptide provides neuroprotection at sub-femtomolar concentrations against toxicity associated with tetrodoxin (electrical blockade), beta-amyloid peptide (Alzheimer's disease neurotoxin), N-methyl-aspartate (excitotoxicity), and human immunodeficiency virus (HIV) envelope protein.

Alternate Names: ADNP, Activity-dependent neuroprotective homeobox protein, Activity-dependent neuroprotective protein, ADNP1

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: Q9H2P0

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ADNP protein.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.