ADRA2C Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14582b
Background:
Alpha-2-adrenergic receptors are members of the Gprotein-coupled receptor superfamily. They include 3 highlyhomologous subtypes: alpha2A, alpha2B, and alpha2C. These receptorshave a critical role in regulating neurotransmitter release fromsympathetic nerves and from adrenergic neurons in the centralnervous system. The mouse studies revealed that both the alpha2Aand alpha2C subtypes were required for normal presynaptic controlof transmitter release from sympathetic nerves in the heart andfrom central noradrenergic neurons. The alpha2A subtype inhibitedtransmitter release at high stimulation frequencies, whereas thealpha2C subtype modulated neurotransmission at lower levels ofnerve activity. This gene encodes the alpha2C subtype, whichcontains no introns in either its coding or untranslated sequences.
Other Names:
Alpha-2C adrenergic receptor, Alpha-2 adrenergic receptor subtype C4, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2CAR, ADRA2C, ADRA2L2, ADRA2RL2
Gene Name: ADRA2C
Gene ID: 152
Primary Accession: P18825
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Alpha-2-adrenergic receptors are members of the Gprotein-coupled receptor superfamily. They include 3 highlyhomologous subtypes: alpha2A, alpha2B, and alpha2C. These receptorshave a critical role in regulating neurotransmitter release fromsympathetic nerves and from adrenergic neurons in the centralnervous system. The mouse studies revealed that both the alpha2Aand alpha2C subtypes were required for normal presynaptic controlof transmitter release from sympathetic nerves in the heart andfrom central noradrenergic neurons. The alpha2A subtype inhibitedtransmitter release at high stimulation frequencies, whereas thealpha2C subtype modulated neurotransmission at lower levels ofnerve activity. This gene encodes the alpha2C subtype, whichcontains no introns in either its coding or untranslated sequences.
Other Names:
Alpha-2C adrenergic receptor, Alpha-2 adrenergic receptor subtype C4, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2CAR, ADRA2C, ADRA2L2, ADRA2RL2
Gene Name: ADRA2C
Gene ID: 152
Primary Accession: P18825
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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