AEBP2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70801
Background:
Adipocyte enhancer-binding protein 2 (AEBP2), also known as zinc finger protein AEBP2, is an 817 amino acid member of the AEBP2 C2H2-type zinc-finger protein family. Localized to the nucleus, AEBP2 acts as a DNA-binding transcriptional repressor of the adipose P2 (aP2) gene. The aP2 gene, which encodes the adipose fatty acid-binding protein, plays a critical role in triglyceride metabolism during adipocyte differentiation. The AE-1 region in the proximal promoter region of the aP2 gene functions as either a positive or negative regulatory element. C/EBPå binds to the AE-1 sequence and functions as a transcriptional activator of aP2, whereas other proteins, such as AEBP2, bind to the region and repress gene expression.
Alternative Name:
AE-binding protein 2, Zinc finger protein AEBP2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100
Specificity: AEBP2 polyclonal antibody detects endogenous levels of AEBP2 protein.
Immunogen:
Recombinant protein of human AEBP2.
MW: ~ 54 kDa
Swis Prot.: Q6ZN18
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Adipocyte enhancer-binding protein 2 (AEBP2), also known as zinc finger protein AEBP2, is an 817 amino acid member of the AEBP2 C2H2-type zinc-finger protein family. Localized to the nucleus, AEBP2 acts as a DNA-binding transcriptional repressor of the adipose P2 (aP2) gene. The aP2 gene, which encodes the adipose fatty acid-binding protein, plays a critical role in triglyceride metabolism during adipocyte differentiation. The AE-1 region in the proximal promoter region of the aP2 gene functions as either a positive or negative regulatory element. C/EBPå binds to the AE-1 sequence and functions as a transcriptional activator of aP2, whereas other proteins, such as AEBP2, bind to the region and repress gene expression.
Alternative Name:
AE-binding protein 2, Zinc finger protein AEBP2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100
Specificity: AEBP2 polyclonal antibody detects endogenous levels of AEBP2 protein.
Immunogen:
Recombinant protein of human AEBP2.
MW: ~ 54 kDa
Swis Prot.: Q6ZN18
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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