AF/LE Purified Anti-Human CD11a Antibody [clone R7-1]

Background:
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Research Area: Cancer, Immunology, Signal transduction, Stem cells

Synonyms:
Integrin alpha-L, LFA-1A, CD11A, ITGAL
Swissprot: P20701

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Concentration: 0.5 mg/mL

Storage:
Store at 2~8°C. Do not freeze.

Alternative for product with catalog number:
301233, 301234