AF/LE Purified Anti-Human CD4 Antibody [clone RPA-T4]

Background:
CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).

Research Area: Cancer, Immunology, Stem cells

Synonyms:
T-cell surface glycoprotein CD4, CD4, T-cell surface antigen T4/Leu-3, CD4
Swissprot: P01730

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Concentration: 0.5 mg/mL

Storage:
Store at 2~8°C. Do not freeze.

Alternative for product with catalog number:
317453, 317454, 300569, 300570