AF/LE Purified Anti-Human/Monkey CD154 Antibody [clone 5C8]

Background:
CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

Research Area: Cancer, Cardiovascular, Immunology

Synonyms:
CD40L, gp39, TRAP, T-BAM, TNFSF5
Swissprot: P29965

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Concentration: 0.5 mg/mL

Storage:
Store at 2~8°C. Do not freeze.