AF/LE Purified Anti-Mouse CD90.2 Antibody [clone 30H12]
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In stock
SKU
E-AB-F10940
Catalog Number: E-AB-F10940
Reactivity: Mouse, Clone: 30H12
Isotype: Rat IgG2b, κ, Conjugation: None (Purified antibody-Azide Free/Low endotoxin)
Applications: Depletion, FCM, IHC
Datasheet, Questions? Contact us!
Reactivity: Mouse, Clone: 30H12
Isotype: Rat IgG2b, κ, Conjugation: None (Purified antibody-Azide Free/Low endotoxin)
Applications: Depletion, FCM, IHC
Datasheet, Questions? Contact us!
Background:
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.
Research Area: Immunology,Neuroscience,Cancer
Synonyms:
Thy-1.2 membrane glycoprotein, Thy1.2, Thy-1.2 antigen, CD90.2, Thy-1.2
Swissprot: P01831
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Concentration: 0.5 mg/mL
Storage:
Store at 2~8°C. Do not freeze.
Alternative for product with catalog number:
105351, 105352
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.
Research Area: Immunology,Neuroscience,Cancer
Synonyms:
Thy-1.2 membrane glycoprotein, Thy1.2, Thy-1.2 antigen, CD90.2, Thy-1.2
Swissprot: P01831
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Concentration: 0.5 mg/mL
Storage:
Store at 2~8°C. Do not freeze.
Alternative for product with catalog number:
105351, 105352
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