AF488 Anti-Human CD62L Antibody [clone DREG56]
€0.00
In stock
SKU
E-AB-F1051L
Catalog Number: E-AB-F1051L
Reactivity: Human, Clone: DREG56
Isotype: Mouse IgG1, κ, Conjugation: AF488
Applications: FCM
Datasheet, Questions? Contact us!
Reactivity: Human, Clone: DREG56
Isotype: Mouse IgG1, κ, Conjugation: AF488
Applications: FCM
Datasheet, Questions? Contact us!
Background:
CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of nave lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
Research Area: Cancer, Cardiovascular, Immunology, Stem cells
Synonyms:
L-selectin, Sell, CD62 antigen-like family member L, LAM-1, LECAM1, Lymph node homing receptor, Ly-22, CD62L, Lnhr, Ly22
Swissprot: P14151
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Alternative for product with catalog number:
304816
CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of nave lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
Research Area: Cancer, Cardiovascular, Immunology, Stem cells
Synonyms:
L-selectin, Sell, CD62 antigen-like family member L, LAM-1, LECAM1, Lymph node homing receptor, Ly-22, CD62L, Lnhr, Ly22
Swissprot: P14151
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Alternative for product with catalog number:
304816
Is Featured? | No |
---|
Write Your Own Review