AF488 Anti-Human CD64 Antibody [clone 10.1]

Background:
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).

Research Area: Immunology

Synonyms:
Fc fragment of IgG high affinity Ia/b/c receptor, CD64A/B/C, CD64, Fc gamma RI, FCGR1A/B/C, IGFR 1
Swissprot: A6NKC4,P12314,Q92637

Buffer: PBS with 0.05% Proclin300, 1% BSA

Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Alternative for product with catalog number:
305010