AF488 Anti-Mouse CD45.2 Antibody [clone 104.2]

Background:
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Synonyms:
Ly-5.2, LCA
Swissprot: P06800

Buffer: PBS with 0.05% Proclin300, 1% BSA

Concentration: 0.5 mg/mL

Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Alternative for product with catalog number:
109815, 109816