AF647 Anti-Human CD35 Antibody [clone E11]

Background:
CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

Research Area: Cancer, Immunology, Stem cells

Synonyms:
Complement receptor type 1, CR1, C3b/C4b receptor, CD35, CR1, C3BR
Swissprot: P17927

Buffer: PBS with 0.05% Proclin300, 1% BSA

Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.