AGMAT polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71636
Background:
Agmatinase (also known as agmatine ureohydrolase) results from the decarboxylation of L-arginine by arginine decarboxylase to form a metabolic intermediate in the biosynthesis of putresine and higher polyamines (spermidine and spermine). Agmatinase has been shown to play a role in several important biochemical processes in humans, ranging from effects on the central nervous system to cell proliferation in cancer and viral replication. Agmatinase catalyzes the hydrolysis of agmatine to putresine and urea and is a major target for drug therapy. Human Agmatinase retains about 30% identity to bacterial agmatinases and less than 20% identity to mammalian arginases. Residues required for binding of Mn2+ at the active site in bacterial Agmatinase and other members of the arginase superfamily are fully conserved in human Agmatinase.
Alternative Name:
Agmatine ureohydrolase, AUH
Application Dilution: WB: 1:500 - 1:2000
Specificity: AGMAT polyclonal antibody detects endogenous levels of AGMAT protein.
Immunogen:
Recombinant protein of human AGMAT
MW: Predicted band size: 38 kDa, Observed band size: Refer to Figures
Swis Prot.: Q9BSE5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Agmatinase (also known as agmatine ureohydrolase) results from the decarboxylation of L-arginine by arginine decarboxylase to form a metabolic intermediate in the biosynthesis of putresine and higher polyamines (spermidine and spermine). Agmatinase has been shown to play a role in several important biochemical processes in humans, ranging from effects on the central nervous system to cell proliferation in cancer and viral replication. Agmatinase catalyzes the hydrolysis of agmatine to putresine and urea and is a major target for drug therapy. Human Agmatinase retains about 30% identity to bacterial agmatinases and less than 20% identity to mammalian arginases. Residues required for binding of Mn2+ at the active site in bacterial Agmatinase and other members of the arginase superfamily are fully conserved in human Agmatinase.
Alternative Name:
Agmatine ureohydrolase, AUH
Application Dilution: WB: 1:500 - 1:2000
Specificity: AGMAT polyclonal antibody detects endogenous levels of AGMAT protein.
Immunogen:
Recombinant protein of human AGMAT
MW: Predicted band size: 38 kDa, Observed band size: Refer to Figures
Swis Prot.: Q9BSE5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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