AGTR1 polyclonal, anti-human, mouse, rat, dog
€385.00
In stock
SKU
250926
Catalog Nr.: 250926
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Receptors and Channels
Pathway and Disease: Endocrine System, Signal Transduction, Signaling Molecules and Interaction
Description:
Type-1 angiotensin II receptor (AGTR1), a receptor for angiotensin II, activates the phosphatidylinositol-calcium second messenger system upon interacting with G proteins. Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD), a severe disorder of renal tubular development.
Alternate Names: Type-1 angiotensin II receptor, AT1, AT1AR, AT1BR, AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P25095
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse AGTR1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Purushothaman K et al. 2012. Elsevier. Cardiovascular Pathology. 22(1)L42-48. PMID# 22749485.
[2] Mateos L et al. Journal of Biological Chemistry. 2011. 286(29): 25574-85. PMID# 21628469.
[3] Shang J. et al. 2013. Chin Med J. 126 (17): 3264-3269. PMID# 24033947.
Pathway and Disease: Endocrine System, Signal Transduction, Signaling Molecules and Interaction
Description:
Type-1 angiotensin II receptor (AGTR1), a receptor for angiotensin II, activates the phosphatidylinositol-calcium second messenger system upon interacting with G proteins. Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD), a severe disorder of renal tubular development.
Alternate Names: Type-1 angiotensin II receptor, AT1, AT1AR, AT1BR, AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P25095
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse AGTR1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Purushothaman K et al. 2012. Elsevier. Cardiovascular Pathology. 22(1)L42-48. PMID# 22749485.
[2] Mateos L et al. Journal of Biological Chemistry. 2011. 286(29): 25574-85. PMID# 21628469.
[3] Shang J. et al. 2013. Chin Med J. 126 (17): 3264-3269. PMID# 24033947.
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