AHCYL1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71444
Background:
AHCYL1 (S-adenosylhomocysteine hydrolase-like 1), also known as DCAL, IRBIT or PRO0233, is an endoplasmic reticulum (ER) protein that is involved in amino acid biosynthesis. Expressed in dentritic blood cells (DCs), AHCYL1 functions to catalyze the H(2)O-dependent conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine, a reaction that uses NAD as a cofactor. Additionally, AHCYL1 contains a PDZ-binding domain and a PEST region through which it can interact with IP3R-I (inositol 1,4,5-trisphosphate (IP3) receptor-I), a protein involved in various signaling pathways. This interaction lowers the affinity of IP3R-1 for its substrate, IP3, thereby decreasing the rate of IP3-IP3R-I binding. AHCYL1 shares 100% homology with its mouse counterpart, indicating a highly conserved function between species. Two isoforms of AHCYL1 are expressed due to alternative splicing events.
Alternative Name:
DCAL, IRBIT, XPVKONA, Adenosylhomocysteinase 2, AdoHcyase 2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: AHCYL1 polyclonal antibody detects endogenous levels of AHCYL1 protein.
Immunogen:
Recombinant protein of human AHCYL1.
MW: ~ 59 kDa
Swis Prot.: O43865
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
AHCYL1 (S-adenosylhomocysteine hydrolase-like 1), also known as DCAL, IRBIT or PRO0233, is an endoplasmic reticulum (ER) protein that is involved in amino acid biosynthesis. Expressed in dentritic blood cells (DCs), AHCYL1 functions to catalyze the H(2)O-dependent conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine, a reaction that uses NAD as a cofactor. Additionally, AHCYL1 contains a PDZ-binding domain and a PEST region through which it can interact with IP3R-I (inositol 1,4,5-trisphosphate (IP3) receptor-I), a protein involved in various signaling pathways. This interaction lowers the affinity of IP3R-1 for its substrate, IP3, thereby decreasing the rate of IP3-IP3R-I binding. AHCYL1 shares 100% homology with its mouse counterpart, indicating a highly conserved function between species. Two isoforms of AHCYL1 are expressed due to alternative splicing events.
Alternative Name:
DCAL, IRBIT, XPVKONA, Adenosylhomocysteinase 2, AdoHcyase 2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: AHCYL1 polyclonal antibody detects endogenous levels of AHCYL1 protein.
Immunogen:
Recombinant protein of human AHCYL1.
MW: ~ 59 kDa
Swis Prot.: O43865
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review