AIFM2 polyclonal, anti-human

Protein Family: Enzymes

Pathway and Disease: Cell Growth and Death

Description:
Apoptosis-inducing factor 2 (AIFM2) is an oxidoreductase, which plays a role in mediating a TP53/p53-dependent apoptosis response. AIFM2 is a caspase-independent mitochondrial effector of apoptotic cell death. AIFM2 binds to DNA in a sequence-independent manner, and contributes to genotoxin-induced growth arrest.

Alternate Names: Apoptosis-inducing factor 2, Apoptosis-inducing factor-like mitochondrion-associated inducer of death, Apoptosis-inducing factor homologous mitochondrion-associated inducer of death, p53-responsive gene 3 protein, AIFM2, AMID, PRG3

Application Notes: E: 1:1,000-1:10,000; WB: 1:100-1:1,000; IHC: 1:50-1:200

Accession No.: Q9BRQ8

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human AIFM2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.