AIFM3 Antibody (C-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP9174b
Background:
This protein encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Other Names: Apoptosis-inducing factor 3, 1---, Apoptosis-inducing factor-like protein, AIFM3, AIFL
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9174b was selected from the C-term region of human AIFM3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q96NN9
Gene ID: 150209
Gene Name: AIFM3
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Vierimaa,O., et.al., J. Endocrinol. Invest. 32 (6), 512-518 (2009)Hahn,M.A., et.al., J. Endocrinol. 201 (3), 387-396 (2009)
This protein encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Other Names: Apoptosis-inducing factor 3, 1---, Apoptosis-inducing factor-like protein, AIFM3, AIFL
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9174b was selected from the C-term region of human AIFM3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q96NN9
Gene ID: 150209
Gene Name: AIFM3
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Vierimaa,O., et.al., J. Endocrinol. Invest. 32 (6), 512-518 (2009)Hahn,M.A., et.al., J. Endocrinol. 201 (3), 387-396 (2009)
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